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Involvement of miltefosine-mediated ERK activation in glioma cell apoptosis through Fas regulation

✍ Scribed by Richa Tewari; Vivek Sharma; Nitin Koul; Ellora Sen

Book ID: 111181081
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 478 KB
Volume: 107
Category: Article
ISSN: 0022-3042
DOI: 10.1111/j.1471-4159.2008.05625.x

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## Abstract Sphingosylphosphorylcholine (SPC) produces reactive oxygen species (ROS) in MS1 pancreatic islet endothelial cells. In the present study, we explored the physiological significance of the SPC‐induced ROS generation in endothelial cells. SPC induced cell death of MS1 cells at higher than