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Involvement of memory T-cells in the pathophysiology of chronic lymphocytic leukemia

✍ Scribed by Correia, Rodolfo Patussi; Silva, Flávia Amoroso Matos; Bacal, Nydia Strachman; Campregher, Paulo Vidal; Hamerschlak, Nelson; Amarante-Mendes, Gustavo P.

Book ID
122802623
Publisher
SciELO
Year
2014
Tongue
English
Weight
230 KB
Volume
36
Category
Article
ISSN
1516-8484

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Using a sensitive immunohistochemical technique and a specific monoclonal antibody (RFD-3), follicular dendritic cells (FDC) have been demonstrated in a significant proportion (6/12) of bone marrow samples from patients with nodular marrow involvement of B-cell chronic lymphocytic leukemia (B-CLL).