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Involvement of Kupffer cells in lipopolysaccharide-induced rapid accumulation of platelets in the liver and the ensuing anaphylaxis-like shock in mice

โœ Scribed by Kouji Yamaguchi; Zhiqian Yu; Hiroyuki Kumamoto; Yumiko Sugawara; Hiroshi Kawamura; Haruhiko Takada; Takashi Yokochi; Shunji Sugawara; Yasuo Endo

Book ID
116270426
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
343 KB
Volume
1762
Category
Article
ISSN
0925-4439

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โœ Shamimunisa B. Mustafa; Brent D. Flickinger; Merle S. Olson ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 208 KB

Excessive nitric oxide (NO) generated by hepatic cells in response to lipopolysaccharide (LPS) and inflammatory substances (e.g., platelet-activating factor [PAF]) is a key contributor to the pathophysiological outcomes observed in the liver during sepsis. In rats subjected to liver-focused endotoxe