Involvement of kinins in hyperresponsiveness induced by platelet activating factor in the human nasal airway
โ Scribed by P J Turner; J W Dear; J C Foreman
- Book ID
- 110004802
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 373 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0007-1188
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๐ SIMILAR VOLUMES
Platelet-activating-factor (PAF) is a potent, biologically active lipid mediator produced by several tissues, including brain. Its role in the central nervous system (CNS) is still unknown, even if its involvement in brain damage and neurotoxicity has been postulated. Its production by neural cells
We have shown that platelet-activating factor (PAF), a weak primary stimulus for neutrophil superoxide generation, synergistically enhances neutrophil oxidative responses to the tumor promoter phorbol myristate acetate (PMA). Since PMA is known to cause cytosol-to-membrane shift of calcium-activated