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Involvement of K+ channels in the relaxant effects of YC-1 in vascular smooth muscle

✍ Scribed by Sabine Seitz; Jörg W Wegener; Johanna Rupp; Makino Watanabe; Andreas Jost; Rolf Gerhard; Asher Shainberg; Rikuo Ochi; Hermann Nawrath

Book ID
114017502
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
337 KB
Volume
382
Category
Article
ISSN
0014-2999

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✍ B. J. Adegunloye; O. A. Sofola; H. A. B. Coker 📂 Article 📅 1993 🏛 Springer 🌐 English ⚖ 345 KB

We have studied the effects of mefloquine on isolated rat aorta. Mefloquine (10(-8) to 1.6 x 10(-4) mol.l-1) relaxed aortic rings precontracted with both noradrenaline (10(-7) mol.l-1) and potassium chloride (60 mmol.l-1). The mefloquine-induced relaxation was somewhat attenuated by removal of the e