Multiple factors contribute to the growth retardation which is a characteristic feature of uncontrolled diabetes. In this report we have examined the effects of streptozotocin-induced (STZ) diabetes on expression of insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-
β¦ LIBER β¦
Involvement of insulin-like growth factor-1 and its binding proteins in proliferation and differentiation of murine bone marrow-derived macrophage precursors
β Scribed by Ezhou Long; Hung T. Huynh; Xin Zhao
- Book ID
- 111638329
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 180 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0969-711X
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Glucocorticoids inhibit the proliferation, but induce the differentiation, of bone marrow stromal cells into osteoblast-like cells. The mechanisms, however, are still conjectural. Since insulin-like growth factors (IGFs) have profound effects on osteoblast growth and differentiation, it is possible