✦ LIBER ✦

Involvement of hepatoma-derived growth factor in the growth inhibition of hepatocellular carcinoma cells by vitamin K2

✍ Scribed by Teruhisa Yamamoto; Hideji Nakamura; Weidong Liu; Ke Cao; Shohei Yoshikawa; Hirayuki Enomoto; Yoshinori Iwata; Noritoshi Koh; Masaki Saito; Hiroyasu Imanishi; Soji Shimomura; Hiroko Iijima; Toshikazu Hada; Shuhei Nishiguchi

Publisher: Springer Japan
Year: 2009
Tongue: English
Weight: 304 KB
Volume: 44
Category: Article
ISSN: 0944-1174
DOI: 10.1007/s00535-008-2304-4

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Vitamin K2 inhibits the growth and invas

Vitamin K2 inhibits the growth and invasiveness of hepatocellular carcinoma cells via protein kinase A activation

✍ Motoyuki Otsuka; Naoya Kato; Run-Xuan Shao; Yujin Hoshida; Hideaki Ijichi; Yukih 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 680 KB

Grb2-associated binder-1 plays a central

Grb2-associated binder-1 plays a central role in the hepatocyte growth factor enhancement of hepatoma growth inhibition by K vitamin analog compound 5

✍ Ziqiu Wang; Lisheng Ge; Meifang Wang; Brian I. Carr 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 711 KB

Compound 5 (Cpd 5), a K vitamin analog, has been shown to inhibit Hep3B human hepatoma cell growth in cultures and rat hepatoma growth in vivo through prolonged epidermal growth factor receptor (EGFR)-extracellular response kinase (ERK) phosphorylation, and hepatocyte growth factor (HGF) synergizes

Synergistic growth inhibition in HL-60 c

Synergistic growth inhibition in HL-60 cells by the combination of acyclic retinoid and vitamin K2

✍ Junichi Kitagawa; Takeshi Hara; Hisashi Tsurumi; Soranobu Ninomiya; Kengo Ogawa; 📂 Article 📅 2010 🏛 Springer-Verlag 🌐 English ⚖ 457 KB

Possible involvement of p21/waf1 in the

Possible involvement of p21/waf1 in the growth inhibition of HepG2 cells induced by hepatocyte growth factor

✍ Nobuyuki Shima; Donna Beer Stolz; Masahiro Miyazaki; Eiichi Gohda; Kanji Higashi 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 202 KB 👁 2 views

Hepatocyte growth factor (HGF) is a potent mitogen for a variety of cell types, but it is also known as an antimitogenic factor for several types of tumor cell lines. The biological processes by which HGF inhibits tumor cell growth remain poorly understood. Here we report a comparative study of HGF-

Involvement of matrix metalloproteinase

Involvement of matrix metalloproteinase type-3 in hepatocyte growth factor-induced invasion of human hepatocellular carcinoma cells

✍ Arnaud Monvoisin; Christèle Bisson; Karim Si-Tayeb; Charles Balabaud; Alexis Des 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 141 KB

## Abstract Intra‐hepatic invasion is a key feature of hepatocellular carcinoma (HCC) progression. We have shown that human liver myofibroblasts induce invasion of HCC cells through Matrigel, via the secretion of hepatocyte growth factor (HGF). In our study, we investigated the role of matrix metal

Growth inhibition of human hepatocellula

Growth inhibition of human hepatocellular carcinoma cells by overexpression of G-protein-coupled receptor kinase 2

✍ Zhengyu Wei; Reginald Hurtt; Michele Ciccarelli; Walter J. Koch; Cataldo Doria 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 578 KB

## Abstract Hepatocellular carcinoma (HCC) is one of the deadliest forms of human liver cancer and does not respond well to conventional therapies. Novel effective treatments are urgently in need. G‐protein‐coupled kinase 2 (GRK2) is unique serine/threonine kinase that involves in many signaling pa