Characterization of bromadiolone resista
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Mette Drude Markussen; Ann-Charlotte Heiberg; Merete Fredholm; Michael Kristense
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Article
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2007
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John Wiley and Sons
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English
β 222 KB
## Abstract The present study characterizes the anticoagulant resistance mechanism in a Danish bromadioloneβresistant strain of Norway rats (__Rattus norvegicus__), with a Y139C VKORC1 mutation. We compared liver expression of the VKORC1 gene, which encodes a protein of the vitamin K 2,3βepoxide re