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Involvement of heme oxygenase-1 in Korean colon cancer

✍ Scribed by Kang, Kyoung Ah; Maeng, Young Hee; Zhang, Rui; Yang, Young Ro; Piao, Mei Jing; Kim, Ki Cheon; Kim, Gi Young; Kim, Young Ree; Koh, Young Sang; Kang, Hee Kyoung; Hyun, Chang Lim; Chang, Weon Young; Hyun, Jin Won

Book ID
118302733
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
464 KB
Volume
33
Category
Article
ISSN
1010-4283

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Heme induces DNA damage and hyperprolife
Heme induces DNA damage and hyperproliferation of colonic epithelial cells via hydrogen peroxide produced by heme oxygenase: A possible mechanism of heme-induced colon cancer
✍ Shin-ichi Ishikawa; Satoru Tamaki; Motoko Ohata; Keizo Arihara; Makoto Itoh πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 339 KB

## Abstract Epidemiological and animal model studies have suggested that high intake of heme, present in red meat, is associated with an increased risk of colon cancer. However, the mechanisms underlying this association are not clear. This study aimed to investigate whether heme induces DNA damage