Crossregulation of NF-κB by the APC/GSK-
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Jiong Deng; Weiya Xia; Stephanie A. Miller; Yong Wen; Hong-Ying Wang; Mien-Chie
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Article
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2004
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John Wiley and Sons
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English
⚖ 322 KB
## Abstract Glycogen synthase kinase‐3β (GSK‐3β) and adenomatous polyposis coli (APC) play an important role in the regulation of β‐catenin. Inhibition of or defects in their functions can lead to activation of β‐catenin. β‐catenin has been recently found to interact with and inhibit nuclear factor