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Involvement of GSK-3β in TWEAK-mediated NF-κB activation

✍ Scribed by Adelheid De Ketelaere; Linda Vermeulen; Jorge Vialard; Inez Van De Weyer; Jean Van Wauwe; Guy Haegeman; Inge Moelans


Book ID
116464451
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
159 KB
Volume
566
Category
Article
ISSN
0014-5793

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## Abstract Glycogen synthase kinase‐3β (GSK‐3β) and adenomatous polyposis coli (APC) play an important role in the regulation of β‐catenin. Inhibition of or defects in their functions can lead to activation of β‐catenin. β‐catenin has been recently found to interact with and inhibit nuclear factor