Involvement of Ets Transcription Factors and Targets in Osteoblast Differentiation and Matrix Mineralization
β Scribed by Calvin P.H. Vary; Vincent Li; Afshin Raouf; Richard Kitching; Ismail Kola; Claudio Franceschi; Marco Venanzoni; Arun Seth
- Book ID
- 115603680
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 263 KB
- Volume
- 257
- Category
- Article
- ISSN
- 0014-4827
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Runx2, osterix, and Ξ²βcatenin are essential for osteoblast differentiation. Runx2 directs multipotent mesenchymal cells to an osteoblastic lineage, and inhibits them from differentiating into the adipocytic and chondrocytic lineages. After differentiating to preosteoblasts, Ξ²βcatenin, o
## Abstract Accumulating data show that oxygen tension can have an important effect on cell function and fate. We used the human preβosteoblastic cell line SVβHFO, which forms a mineralizing extracellular matrix, to study the effect of low oxygen tension (2%) on osteoblast differentiation and miner