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Involvement of endothelium and endothelin-1 in lead-induced smooth muscle cell dysfunction in rats

✍ Scribed by Molero, L; Carrasco, C; Marques, M; Vaziri, N D; Mateos-Cáceres, P J; Casado, S; Macaya, C; Barrientos, A; López-Farré, A J

Book ID
110052496
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
153 KB
Volume
69
Category
Article
ISSN
0085-2538

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## Abstract Insulin is known to cause an increase in endothelin‐1 (ET‐1) receptors in vascular smooth muscle cells (SMCs), but the effect of insulin‐like growth factor 1 (IGF‐1) on ET‐1 receptor expression is not known. We therefore carried out the present study to determine the effect of IGF‐1 on