Involvement of EGF receptor and c-Src in the survival signals induced by TGF-β1 in hepatocytes
✍ Scribed by Murillo, Miguel M; Castillo, Gaelle del; Sánchez, Aránzazu; Fernández, Margarita; Fabregat, Isabel
- Book ID
- 110069712
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 314 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
In mouse C3H 10T1/2 cells, we previously reported that TGF-beta1 first delays and later potentiates EGF-induced DNA synthesis corresponding to an inhibition of EGF-induced cyclin D1 expression at t = 13 h. We report here that in accord with DNA synthesis kinetics, TGF-beta1 initially suppresses EGF-
Ursodeoxycholic acid (UDCA) inhibits classical mitochondrial pathways of apoptosis by either directly stabilizing mitochondrial membranes or modulating specific upstream targets. Furthermore, UDCA regulates apoptosis-related genes from transforming growth factor 1 (TGF-1)-induced hepatocyte apopto