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Involvement of E-cadherin, β-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma

✍ Scribed by M.G. Tucci; G. Lucarini; D. Brancorsini; A. Zizzi; A. Pugnaloni; A. Giacchetti; G. Ricotti; G. Biagini

Book ID
108669735
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
942 KB
Volume
157
Category
Article
ISSN
0007-0963

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Much progress has been made in identifying genes mutated during the development of colorectal carcinoma. Mutation of the APC gene in particular appears to be fundamental for colorectal tumour initiation. In contrast, loss of expression of E-cadherin appears to be a late event, which may be important