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Involvement of dopamine (DA)/serotonin (5-HT)/sigma (σ) receptor modulation in mediating the antidepressant action of ropinirole hydrochloride, a D2/D3 dopamine receptor agonist

✍ Scribed by Ashish Dhir; S.K. Kulkarni


Book ID
116326597
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
270 KB
Volume
74
Category
Article
ISSN
0361-9230

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Herein, we evaluate the interaction of the ␣ 2 -AR antagonist, yohimbine, as compared to fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of adrenergic, dopaminergic and serotonergic transmission in freelymoving rats. Yohimbine displays marked affinity at hum