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Involvement of cytochrome P-450 in Δ22-desaturation in ergosterol biosynthesis of yeast

✍ Scribed by Shingo Hata; Tokuzo Nishino; Masayuki Komori; Hirohiko Katsuki

Book ID
118315850
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
303 KB
Volume
103
Category
Article
ISSN
0006-291X

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Coexpression in yeast of Taxus cytochrom
Coexpression in yeast of Taxus cytochrome P450 reductase with cytochrome P450 oxygenases involved in Taxol biosynthesis
✍ Stefan Jennewein; Hangil Park; JingHong M. DeJong; Robert M. Long; Arthur P. Bol 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 545 KB

## Abstract To maximize redox coupling efficiency with recombinant cytochrome P450 hydroxylases from yew (__Taxus__) species installed in yeast for the production of the anticancer drug Taxol, a cDNA encoding NADPH:cytochrome P450 reductase from __T. cuspidata__ was isolated. This single‐copy gene