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Involvement of Clusterin and the Aggresome in Abnormal Protein Deposits in Myofibrillar Myopathies and Inclusion Body Myositis

✍ Scribed by I. Ferrer; M. Carmona; R. Blanco; D. Moreno; B. Torrejón-Escribano; M. Olivé

Book ID
111404341
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
389 KB
Volume
15
Category
Article
ISSN
1015-6305

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## Abstract Accumulation of β‐amyloid protein (Aβ) occurs in some muscle fibers of patients with inclusion body myopathy and resembles the type of amyloid deposits seen in the affected tissues of patients with Alzheimer's disease and cerebrovascular amyloidosis. Because mutations in exons 16 and 17