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Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes

✍ Scribed by Lang, K S; Myssina, S; Brand, V; Sandu, C; Lang, P A; Berchtold, S; Huber, S M; Lang, F; Wieder, T

Book ID
110016633
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
342 KB
Volume
11
Category
Article
ISSN
1350-9047

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Ceramide is a sphingolipid that has been implicated both in apoptosis and protection from cell death. We show that in both rat cerebellar granule cells and cortical neuronal cultures application of C(2)-ceramide causes cell death in a dose- and time-dependent manner. Similar effects were observed wi