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Involvement of cAMP in CD3 T cell receptor complex- and CD2-mediated apoptosis of human thymocytes

✍ Scribed by Frank Mentz; M. Djavad Mossalayi; Fateh Ouaaz; Patrice Debré


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
431 KB
Volume
25
Category
Article
ISSN
0014-2980

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Apoptosis represents the main mechanism involved in the intrathymic cell selection. The involution and atrophy of the thymic gland during aging has been associated with an altered representation of thymocyte subsets and particularly of CD4 ؉ CD8 ؉ double-positive (DP) thymocytes, i.e., the cell popu