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Involvement of cAMP-dependent protein kinase and pH on the regulation of cardiac sarcoplasmic reticulum

✍ Scribed by Evangelia G. Kranias; Frederic Mandel; Arnold Schwartz

Book ID
118314472
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
373 KB
Volume
92
Category
Article
ISSN
0006-291X

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Canine cardiac sarcoplasmic reticulum is phosphorylated by adenosine 3',5'-monophosphate (cAMP)-dependent and by calcium.calmodulin-dependent protein kinases on a 27,000 proteolipid, called phospholamban. Both types of phosphorylation are associated with an increase in the initial rates of Ca2+ tran