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Involvement of Calcineurin in Ischemic Myocardial Damage

✍ Scribed by Ashakumary Lakshmikuttyamma; Ponniah Selvakumar; Anil Ratan Sharma; Rajendra K. Sharma

Publisher: Springer
Year: 2011
Tongue: English
Weight: 220 KB
Volume: 14
Category: Article
ISSN: 1061-1711
DOI: 10.1007/s00547-005-2005-2

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## Abstract Calcineurin (CaN) has been reported as a critical mediator for cardiac hypertrophy and cardiac myocyte apoptosis. In the present study, we investigated the activity and expression of CaN and the effect of calpain in rat heart after ischemia and reperfusion. Rat ischemic heart showed sig