Involvement of arachidonic acid in chemical stress-induced interleukin-6 synthesis in osteoblast-like cells: comparison with heat shock protein 27 induction

Protein kinase C activation inhibits str

Protein kinase C activation inhibits stress-induced synthesis of heat shock protein 27 in osteoblast-like cells: Function of arachidonic acid

✍ Atsushi Suzuki; Osamu Kozawa; Yutaka Oiso; Kanefusa Kato 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 616 KB

Exposure of osteoblast-like MC3T3-El cells to sodium arsenite (arsenite) increased the level of heat shock protein 27 (hsp27). The effect of arsenite was dose-dependent in the range of 50 to 200 pM. Arsenite also stimulated arachidonic acid release dose-dependently in the range between 50 and 200 pM