𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Involvement of Akt/NF-κB pathway in antitumor effects of parthenolide on glioblastoma cells in vitro and in vivo

✍ Scribed by Hiromichi Nakabayashi, Keiji Shimizu

Book ID
119897495
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
773 KB
Volume
12
Category
Article
ISSN
1471-2407

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Involvement of Akt/NF-κB pathway in N6-i
Involvement of Akt/NF-κB pathway in N6-isopentenyladenosine-induced apoptosis in human breast cancer cells
✍ Chiara Laezza; Anna M. Malfitano; Tiziana Di Matola; Paolo Ricchi; Maurizio Bifu 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB

## Abstract __N__^6^‐isopentenyladenosine (i6A) inhibits the tumor cell growth by inducing cell apoptosis in various cancer cell lines. However, little is known regarding the mechanisms by which the drug induces cell apoptosis. In this study, we further explored the molecular mechanisms of i6A as a

A novel NF-κB inhibitor DHMEQ selectivel
A novel NF-κB inhibitor DHMEQ selectively targets constitutive NF-κB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo
✍ Mariko Watanabe; Md. Zahidunnabi Dewan; Takamitu Okamura; Masataka Sasaki; Kinji 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 453 KB

Multiple myeloma (MM) is a fatal lymphoid malignancy that is incurable with conventional modalities of chemotherapy. Strong and constitutive activation of nuclear factor kappa B (NF-kappaB) is a common characteristic of MM cells. In our study we successfully target NF-kappaB with a novel NF-kappaB i

The effect of focal adhesion kinase gene
The effect of focal adhesion kinase gene silencing on 5-fluorouracil chemosensitivity involves an Akt/NF-κB signaling pathway in colorectal carcinomas
✍ Yuying Chen; Zhanxiang Wang; Pingan Chang; Liuxin Xiang; Feng Pan; Jianjun Li; J 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 708 KB

## Abstract Multicellular resistance (MCR) is produced because multicellular spheroids (MCSs) are formed with a broad cell–cell connection when cultured in three‐dimensions, which limits the clinical treatment efficacy in solid tumors. Focal adhesion kinase (FAK) plays an important role in apoptosi