Involvement of A3 receptors in the potentiation by adenosine of the inhibitory effect of theophylline on human eosinophil degranulation: possible novel mechanism of the anti-inflammatory action of theophylline

A STUDY OF THE EFFECT OF THEOPHYLLINE ON

A STUDY OF THE EFFECT OF THEOPHYLLINE ON THE ANTI-INFLAMMATORY POTENCY OF DEXAMETHASONE USING α-AMINOISOBUTYRIC ACID UPTAKE IN RAT SKIN FIBROBLASTS: A POSSIBLE MECHANISM THROUGH THE GLUCOCORTICOID RECEPTOR

✍ K. Xenos; D. Kalogeromitros; Sophia L. Markantonis; A. Katsambas; Alexandra Kats 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 209 KB

The action of theophylline on the uptake of alpha-aminoisobutyric acid (AIB; an indicator of anti-inflammatory potency) stimulated by the glucocorticoid, dexamethasone, in cultured rat fibroblast monolayers was evaluated. Theophylline alone (0.1 m m) did not show significant activity (3314+/-27 cpm)