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Involvement of 5-lipoxygenase metabolites of arachidonic acid in cyclic AMP-stimulated steroidogenesis and steroidogenic acute regulatory protein gene expression

✍ Scribed by Xing Jia Wang; Matthew T Dyson; Youngah Jo; Darrell W Eubank; Douglas M Stocco


Book ID
117668540
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
196 KB
Volume
85
Category
Article
ISSN
0960-0760

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## Abstract Steroidogenic acute regulatory protein (StAR) plays a key role in the availability of cholesterol to the inner mitochondrial membrane, where the first step of steroidogenesis, its conversion to pregnenolone, takes place. Here, we demonstrate for the first time that the StAR gene is also