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Involvement of 5-HT3 receptors in the nucleus accumbens in the potentiation of cocaine-induced behaviours in the rat

✍ Scribed by Sonja Herges; David A Taylor

Book ID
110005363
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
168 KB
Volume
131
Category
Article
ISSN
0007-1188

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Cocaine induces an increase in hippocampal and nucleus accumbens (Nac) serotonin (5-HT) concentration parallel to locomotor activation. Both effects can be modulated by systemic 5-HT 1A -receptor agonism/antagonism. Given the contribution of the hippocampus to spontaneous behavioral activity, these