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Invitro receptor specificity of the 5HT1A selective phenylpiperazine, LY165163

✍ Scribed by Marlene L. Cohen; Norman Mason; Kathryn W. Schenck


Book ID
118341919
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
317 KB
Volume
39
Category
Article
ISSN
0024-3205

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Pharmacological profile of LY301317, a p
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LY301317 ((4r)-(-)-4-(dipropylamino)-6-(5-oxazolinyl)-1, 3,4,5-tetrahydrobenz[c,d]indole) has high affinity for the 5-HT 1A receptor and weak affinity for the 5-HT 1D and histamine-H 1 receptors. No significant affinity was found for the other amine receptors studied. In rats, LY301317 produced pote