Investigations of New Pyridazinone Derivatives for the Synthesis of Potent Analgesic and Anti-Inflammatory Compounds with Cyclooxygenase Inhibitory Activity

Synthesis and Analgesic and Anti-inflamm

Synthesis and Analgesic and Anti-inflammatory Activity of Some New (6-Acyl-2-benzoxazolinone and 6-Acyl-2-benzothiazolinone Derivatives with Acetic Acid and Propanoic Acid Residues

✍ Serdar Ünlü; Tijen Önkol; Yasemin Dündar; Berna Ökçelik; Esra Küpeli; Erdem Yeşi 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 162 KB 👁 2 views

## Abstract In this study for developing potent analgesic and anti‐inflammatory compounds, we synthesized 6‐acyl‐2‐benzoxazolinone and 6‐acyl‐2‐benzothiazolinone derivatives with acetic acid and propanoic acid side chain, and performed preliminary screening of their __in vivo__ analgesic and anti‐i