Investigations of Free Anthraquinones from Rhubarb Against α-Naphthylisothiocyanate-induced Cholestatic Liver Injury in Rats

Characterization of the protective effec

Characterization of the protective effects of melatonin and related indoles against α-naphthylisothiocyanate-induced liver injury in rats

✍ J.R. Calvo; R.J. Reiter; J.J. García; G.G. Ortiz; D.X. Tan; M. Karbownik 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 218 KB 👁 2 views

The protective effect of melatonin, 6-hydroxymelatonin and N-acetylserotonin against alpha-naphthylisothiocyanate (ANIT)-induced liver injury was investigated and compared in rats injected once with the hepatotoxicant (75 mg/kg body weight). In rats injected with ANIT alone, liver injury with choles