Investigations into the total synthesis of momilactones. Stereoselective preparation of (±)-4,4-dinor-9βH-pimara-7,19-diene

Stereospecific preparation of (±)-4,4-di

Stereospecific preparation of (±)-4,4-dinor-9βH-pimara-7,15-diene, a model for the total synthesis of momilactone type diterpenes

✍ A. Sicherer-Roetman; B.J.M. Jansen; Ae. de Groot 📂 Article 📅 1984 🏛 Elsevier Science 🌐 French ⚖ 201 KB

The synthesis of (+)-4,4-dinor-9BH-pimara-7,15-diene, 4, a model compound for momilactones, has been achieved via stereospecific Diels-Alder reaction and alkylation. The fungitoxic momilactone diterpenes (eg. momilactone A, 2) form a class of rather unusual natural products, possessing a trans-syn h