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Investigations into the Folkloric Antimicrobial Activities of Landolphia owrrience

✍ Scribed by G. C. Ebi; S. I. Ofoefule

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 77 KB
Volume: 11
Category: Article
ISSN: 0951-418X
DOI: 10.1002/(sici)1099-1573(199703)11:2<149::aid-ptr43>3.0.co;2-n

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✦ Synopsis

The folkloric antimicrobial activities of Landolphia owrrience were investigated using ether, ethylacetate and nbutanol extracts of the leaves as well as six TLC components (A-F) of the n-butanol extract. The activities of these extracts and TLC components were investigated against Escherichia coli, Bacillus subtilis, Candida albicans and Aspergillus niger using the agar diffusion method.

The n-butanol fraction as well as its TLC fractions showed marked antimicrobial activities against the four organisms. The n-butanol extract was active against all the organisms except B. subtilis. The TLC fractions A, D and E showed similar antimicrobial spectra and were active against E. coli, B. subtilis and C. albicans. Fractions B and F possessed similar antimicrobial spectra, showing activity against B. subtilis and C. albicans. Fractions B and F have the greatest fungicidal activity while fraction A has the greatest antibacterial activity based on the MIC results.

These activities have been attributed to the presence of steroids, saponins, tannins and saponins probably as glycosides.

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