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Investigational cancer drugs targeting cell metabolism in clinical development

โœ Scribed by Sborov, Douglas W; Haverkos, Bradley M; Harris, Pamela J

Book ID
126459477
Publisher
Informa plc
Year
2014
Tongue
English
Weight
759 KB
Volume
24
Category
Article
ISSN
1354-3784

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## Abstract The past decade has seen the emergence of a new mechanistic paradigm of cancer therapeutics. Not only have mitochondria taken centre stage as key cellular organelles mediating intrinsic pathways of cell death by apoptosis, but nonapoptotic pathways have also been shown to involve mitoch