The Frog Embryo Teratogenesis Assay: Xenopus (FETAX) bioassay has been employed extensively to screen compounds for teratogenic activity. Recent laboratory studies have indicated that low potassium concentrations retard Xenopus laevis development. The effects of varying concentrations of minerals on
Investigation of the teratogenic potential of ochratoxin A and B using the FETAX system
β Scribed by E. O'Brien; A. Prietz; Daniel R. Dietrich
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 158 KB
- Volume
- 74
- Category
- Article
- ISSN
- 1542-9733
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## Abstract The aim of this study was to find out whether very low doses of nephrotoxic and hepatotoxic mycotoxins ochratoxin A (OTA) and fumonisin B~1~ (FB~1~) induce oxidative stress in rat kidney and liver and whether their effect is synergistic. Rats were treated orally with OTA (5 ng/kg b.w. a