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Investigation of the Substrate Recognition of Drosophila melanogaster Nucleoside Kinase by Site Directed Mutagenesis

โœ Scribed by Solaroli, N.; Bjerke, M.; Johansson, M.; Karlsson, A.

Book ID
126627285
Publisher
Taylor and Francis Group
Year
2004
Tongue
English
Weight
96 KB
Volume
23
Category
Article
ISSN
0732-8311

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โœ Paul Holloway; Kyle L. Knoke; Jack T. Trevors; Hung Lee ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 58 KB ๐Ÿ‘ 1 views

We attempted to expand the range of chlorinated solvents degraded by Xanthobacter autotrophicus GJ10 to include trichloroethylene by the rational modification of the enzyme haloalkane dehalogenase. The amino acids Phe164, Asp170, Phe172 and Trp175 were individually replaced with alanine by site-dire