Investigation of the one-pot synthesis of quinolin-2-(1H)-ones and the discovery of a variation of the three-component Ugi reaction
β Scribed by Gordon, Christopher P.; Young, Kelly A.; Hizartzidis, Lacey; Deane, Fiona M.; McCluskey, Adam
- Book ID
- 118210268
- Publisher
- Royal Society of Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 277 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1477-0520
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## Abstract An efficient synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives by one-pot three-component condensation reaction between an alkyl or aryl aldehyde, a 1,3-dicarbonyl compound, and urea or thiourea in the presence of catalytic amount of bromodimethylsulfonium bromide has been develo
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