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Investigation of the mechanisms underlying the hypophagic effects of the 5-HT and noradrenaline reuptake inhibitor, sibutramine, in the rat

✍ Scribed by Helen C. Jackson; M. Clair Bearham; Lisa J. Hutchins; Sarah E. Mazurkiewicz; Andrew M. Needham; David J. Heal


Book ID
110003096
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
353 KB
Volume
121
Category
Article
ISSN
0007-1188

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✍ A. M. J. Montgomery; M. J. Burton πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 619 KB

Systemic administration of serotonin (5-hydroxytryptamine, 5-HT) to non-deprived rats increased saline (0.9%) consumption (5-HT hyperdipsia), without altering saline preference in two-bottle test. When sodium saccharin (0.1%) was the test solution 5-HT suppressed both consumption and preference. 5-H