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Investigation of the ligand binding site of the C5a receptor

✍ Scribed by T. Vogt; S. Zahn; T. Hebeil; B. Fischer; O. Götze


Book ID
118384870
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
131 KB
Volume
30
Category
Article
ISSN
0161-5890

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Binding of biotin-Csa to the C5a receptor in membrane fragments followed by detergent solubilization and purification with streptavidin-agarose affinity chromatography resulted in the isolation of a receptor complex with associated G-proteins. In contrast, when receptor was detergent-solubilized in