Investigation of the direction of the Fischer cyclization of arylhydrazones that are derivatives of hexahydrobenz[e]indene cyclization of a piperidine-2,3-dione 3-hydrazone

Total Synthesis of [3aS-(3aα,9aα,9bβ)]-3

Total Synthesis of [3aS-(3aα,9aα,9bβ)]-3a,4,5,9,9a,9b-Hexahydro-3a,6-dimethyl-1H-benz[e]indene-3,7(2H,8H)-dione and Derivatives, Building Blocks for the Synthesis of Glucocorticoids

✍ Daniewski, Andrzej Robert ;Piotrowska, Emilia ;Wojciechowska, Wanda 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 417 KB 👁 1 views

The natural and synthetic glucocorticoids are very important compounds commonly used as drugs against many diseases. Recently, we have reported the synthesis of some of the title compounds and their transformations into 6-methyl-5-androstene-3,11,17-trione 3-ethyleneacctal, a building block for the