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Investigation of substituted 6-aminohexanoates as skin penetration enhancers

โœ Scribed by Katerina Brychtova; Lenka Dvorakova; Radka Opatrilova; Ivan Raich; Sandra Kacerova; Lukas Placek; Danuta S. Kalinowski; Des R. Richardson; Josef Jampilek

Book ID
113495603
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
485 KB
Volume
20
Category
Article
ISSN
0968-0896

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Esters of 6-aminohexanoic acid as skin p
Esters of 6-aminohexanoic acid as skin permeation enhancers: The effect of branching in the alkanol moiety
โœ Alexandr Hrabรกlek; Katerฬ†ina Vรกvrovรก; Pavel Dolezฬ†al; Miloลก Machรกcฬ†ek ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 114 KB

In order to investigate the effect of branching and cyclization in the hydrophobic part of skin permeation enhancers, 17 novel branched-chain and cyclic 6-aminohexanoic acid esters were prepared. Their permeation enhancing activity was evaluated in vitro using human skin and theophylline as a model