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Investigation of regioselectivity in the synthesis of spiro [pyrrolidine-2,3′-oxindoles] by use of the Huisgen reaction

✍ Scribed by Chen, Gang; Miao, Yan-qing; Zhou, Rui; Zhang, Li; Zhang, Jie; Hao, Xiao-jiang

Book ID
115471183
Publisher
Springer Netherlands
Year
2012
Tongue
English
Weight
233 KB
Volume
39
Category
Article
ISSN
0922-6168

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## Abstract The spiro[pyrrolidine‐3,3′‐oxindole] ring system is found at the core of a number of alkaloids, which possess significant biological activity and are interesting, challenging targets for chemical synthesis. In the present review, we report on the different strategies for the synthesis o