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Investigation of rat mast cell degranulation using flow cytometry

✍ Scribed by Mauro Perretti; Sandra Nuti; Luca Parente


Book ID
116097147
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
504 KB
Volume
23
Category
Article
ISSN
0160-5402

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Background: Mast cells are primary mediators of allergic inflammation. Antigen-mediated crosslinking of their cell surface immunoglobulin E (IgE) receptors results in degranulation and the release of proinflammatory mediators including histamine, tumor necrosis factor-␣, and leukotrienes. Methods: M