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Investigation of possible pharmacokinetic and pharmacodynamic interactions between epanolol and digoxin

✍ Scribed by R. A. Lefebvre; M. G. Bogaert; D. Duprez

Publisher
Springer
Year
1990
Tongue
English
Weight
358 KB
Volume
38
Category
Article
ISSN
0031-6970

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✍ R. A. Lefebvre; G. Wilde; M. T. Rosseel; D. Duprez; J. Sutter; F. Pocchiari πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 362 KB

The possibility of a pharmacokinetic interaction between isosorbide-5-mononitrate (5-ISMN) and epinine, the active metabolite of ibopamine, has been investigated in 8 healthy male subjects given single doses of 200 mg ibopamine and 20 mg 5-ISMN, separately and together. The plasma 5-ISMN concentrati