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Investigation of Conditions Giving Minimal Scrambling in the Synthesis of trans-Porphyrins from Dipyrromethanes and Aldehydes

โœ Scribed by Littler, Benjamin J.; Ciringh, Yangzhen; Lindsey, Jonathan S.


Book ID
111939137
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
109 KB
Volume
64
Category
Article
ISSN
0022-3263

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One-flask synthesis of meso-substituted
โœ Chang-Hee Lee; Jonathan S. Lindsey ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 985 KB

The reaction at room temperature of an aldehyde with excess pyrrole in the absence of solvent affords the meso-substituted dipyrromethane. The reaction is catalyzed with trifluoroacetic acid or with BF9,0(Et)2. The dipyrromethaue is purified by crystallixation or by flash chromatography on silica wi