𝔖 Bobbio Scriptorium
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Investigation of Binding of Inhibitors to Ribonuclease by NMR Spectroscopy

✍ Scribed by Dr. H. Rüterjans


Book ID
101549057
Publisher
John Wiley and Sons
Year
1969
Tongue
English
Weight
264 KB
Volume
8
Category
Article
ISSN
0044-8249

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Ribonuclease A (RNase A) and the ribonuclease inhibitor protein (RI) form one of the tightest known protein-protein complexes. RNase A variants and homologues, such as G88R RNase A, that retain ribonucleolytic activity in the presence of RI are toxic to cancer cells. Herein, a new and facile assay i