Investigation into the role of Fibroblast Growth Factor 8 and its receptor, FGFR3, in the murine allantois
β Scribed by Dexter X. Jin; Karen M. Downs
- Book ID
- 116977407
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 51 KB
- Volume
- 331
- Category
- Article
- ISSN
- 0012-1606
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Fibroblast growth factors may play an important role in the differential growth of the skull, brain, and facial prominences. In order to understand the role of FGFs in vivo, we have analyzed the competency of head mesenchyme to respond to FGFs via expression of the high affinity receptors FGFR1, 2,
Identification of FGFR3 mutations in 28 achondroplasia patients, in 10 of 18 cases of hypochodroplasia and in both cases with type I TD, is reported here. To detect mutations of achondroplasia, both natural restriction site and amplification created restriction site (ACRS) were utilized. Mutation 11