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Investigating the effects of stereochemistry on incorporation and removal of 5-fluorocytidine analogs by mitochondrial DNA polymerase gamma: comparison of d- and l-D4FC-TP

✍ Scribed by Eisuke Murakami; Adrian S. Ray; Raymond F. Schinazi; Karen S. Anderson

Book ID
113457107
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
154 KB
Volume
62
Category
Article
ISSN
0166-3542

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Effects of β-D-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine 5′-triphosphate (β-D-D4FC-TP) and its β-L-enantiomer 5′-triphosphate (β-L-D4FC-TP) on viral DNA polymerases: A. Faraj1, R.F. Schinazi2, A. Joudawlkis2, Z. Lesnikowski2, A. McMillan2, C.D. Morrow1 and J.-P. Sommadossi1. University of Alabama at Birmingham, Birmingham, AL, USA1 and VA Medical Center/Emory University, Decatur, GA, USA2
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