Inverted urothelial papilloma : Is ploidy, MIB-1 proliferative activity, or p53 protein accumulation predictive of urothelial carcinoma?
✍ Scribed by John C. Cheville; Kevin Wu; Thomas J. Sebo; Liang Cheng; Darren Riehle; Christine M. Lohse; V. Shane Pankratz
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 265 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
BACKGROUND.
Inverted urothelial papilloma is an unusual neoplasm of the urinary tract. Although the association between inverted urothelial papilloma and urothelial carcinoma is not entirely clear, many studies indicate that patients with inverted papilloma are at increased risk for the development of urothelial carcinoma. In addition, aneuploid inverted papillomas have been associated with the subsequent development of urothelial carcinoma. The objective of this study was to determine whether ploidy, MIB-1 proliferative activity, or p53 protein staining in inverted papilloma were predictive of urothelial carcinoma.