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Inverse Peptide Synthesis via Activated α-Aminoesters

✍ Scribed by Suppo, Jean-Simon; Subra, Gilles; Bergès, Matthieu; Marcia de Figueiredo, Renata; Campagne, Jean-Marc

Book ID
121730488
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
668 KB
Volume
53
Category
Article
ISSN
0044-8249

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Functionalizod dia~lzinc reagents, easily available from the corresponding aryl halides by a halogen-lithium exchange followed by transmetalation with ZnCI 2 react with a glycine cation equivalent to afford substituted a-aryl a-amino esters in good yields.