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Inverse-electron-demand Diels-Alder reactions of Fischer carbene complexes: a new and efficient dihydrobenzene synthesis via a retrocycloaddition of chromium hexacarbonyl

✍ Scribed by Wang, Siu Ling B.; Wulff, William D.


Book ID
120838764
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
408 KB
Volume
112
Category
Article
ISSN
0002-7863

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## Abstract Hormone‐refractory prostate cancer (HRPC), insensitive to most cytostatic interventions, features low response rates and bad prognosis. Studies with HRPC treated with temozolomide (TMZ) showed a poor response and the results were discouraging. Therefore, TMZ has been considered to be in