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Invasiveness of Hepatocellular Carcinoma Cell Lines: Contribution of Membrane-Type 1 Matrix Metalloproteinase

✍ Scribed by Murakami, Koji; Sakukawa, Rieko; Ikeda, Takashi; Matsuura, Tomokazu; Hasumura, Satoshi; Nagamori, Seishi; Yamada, Yuji; Saiki, Ikuo

Book ID: 122314844
Publisher: Neoplasia Press
Year: 1999
Tongue: English
Weight: 331 KB
Volume: 1
Category: Article
ISSN: 1522-8002
DOI: 10.1038/sj.neo.7900046

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## Abstract Intra‐hepatic invasion is a key feature of hepatocellular carcinoma (HCC) progression. We have shown that human liver myofibroblasts induce invasion of HCC cells through Matrigel, via the secretion of hepatocyte growth factor (HGF). In our study, we investigated the role of matrix metal